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A technique for the simultaneous staining of both nucleolar organizer regions and kinetochores of human chromosomes with silver. |
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| Authors: | T E Denton W R Brooke W M Howell |
| Abstract: | Pretreatment of human metaphase chromosomes with NaOH at a pH of 8.5, followed by staining with silver nitrate, differentially stains both the nucleolar organizer regions on the 10 acrocentric chromosomes as well as the kinetochore centers on all 46 chromosomes. |
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