Inhibition of erythrocyte ghost ATPase by polyene antibiotics |
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| Authors: | E Capuozzo S Jullien C Salerno C Crifò |
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| Affiliation: | Department of Biochemical Sciences, University of Rome, Italy. |
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| Abstract: | The effect of micromolar concentrations of polyene antibiotics on erythrocyte ghost ATPase activities has been studied. (Mg2+)-ATPase is inhibited by amphotericin B and amphotericin B methyl ester, whereas (Na+ + K+ + Mg2+)-ATPase is inhibited by amphotericin B and lucensomycin. (Ca2+ + Mg2+)-ATPase is only slightly affected by polyene antibiotics. |
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