Optical trap as a tool for studying motor proteins |
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Authors: | S R Nabiev D A Ovsyannikov B Y Bershitsky S Y Bershitsky |
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Institution: | (1) Institute of Immunology and Physiology, Ural Division, Russian Academy of Sciences, ul. Pervomaiskaya 91, Yekaterinburg, 620041, Russia |
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Abstract: | The review briefs the optical trap method, a modern experimental tool based on the recently discovered ability of light to trap and hold micron and submicron particles in a focused beam. The physical principle underlying the optical trap and the opportunities that it provides for studying the molecular nature of biological motility are considered. Several studies into the physical characteristics and functions of single motor protein molecules performed using the optical trap and recording nanometer displacements and piconewton forces are analyzed. |
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Keywords: | optical trap method physical principles motor proteins mechanical characteristics |
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