Dynamics of EEG-indicators in alcohol abstinence

To study the possibility of discrimination of different periods of alcohol abstinence state (acute, subacute, and arrested) the brain electrical activity of 30 patients with chronic alcoholism was recorded from 24 sites of convexital scalp surface during the detoxication. The "Synchro-EEG" program package was applied for EEG processing using 840 parameters. Sets of state-specific characters were selected, and an integral parameter for estimation of the brain functional state was developed. Parameters of coherence of biopotentials in narrow frequency subbands turned to be of the greatest informative value. As compared to the normal state, in the acute period all the frequency components were changed. Their dynamics during detoxication was different. Delta and theta activity were normalized faster then the alpha and beta frequencies. The dynamics of the spatial synchronization foci reflected the recovery of consciousness and normalization of the brain functional state.