不同周龄Balb／c小鼠脏器质量及其变化趋势分析

目的：测定不同周龄Balb／c小鼠主要脏器质量、脏器系数，并进行比较。方法：取120只3周龄、5周龄、7周龄的Balb／c小鼠，雌雄各半，精确测量小鼠体重和主要脏器质量，计算脏器系数。结果：①雌性与雄性Balb／c小鼠脏器质量相比较：3周龄时肝、脾有显著差异（P〈0．05）；5周龄时肝有非常显著差异（P〈0．01），脾、肺有显著差异（P〈0．05）；7周龄时肝、肺及双肾有非常显著差异（P〈0．01），心、脾有显著差异（P〈0．05）。②雌性与雄性Balb／c小鼠脏器系数相比较：3周龄时肝、脾有显著差异（P〈0．05）；5周龄时肝、脾有非常显著差异（P〈0．01），膀胱有显著差异（P〈0．05）；7周龄时肺、双肾有非常显著差异（P〈0．01），脾、膀胱有显著差异（P〈0．05）。结论：随着周龄的增长，Balb／c雌、雄性小鼠之间，存在差异的脏器也在增多。

Measurement and Change Trend Analysis of Organ Weights in Balb/c Mice of Different Ages

Objective： To measure and compare the weight of main organs and the organ coefficient between male and female Balb/c mice of different ages. Methods： 20 male and 20 female Balb/c mice at the ages of 3 weeks, 5 weeks and 7 weeks （total 120 mice） were used for the measurement of weight of main organs and organ coefficient. Results： 1. Comparing the organ weight between female and male Balb/c mice, significant difference （P〈0.05） for liver or spleen of mice of 3 weeks old, distinct significant differences （P〈0.01） for liver and significant differences （P〈0.05） for spleen or lungs of mice of 5 weeks old, distinct significant differences （P〈0.01） for liver, lungs or double kidneys and significant differences （P〈0.05） for heart or spleen of mice of 7 weeks old Balb/c were observed in the study. 2. Comparing the organ coefficient between female and male Balb/c mice, significant differences （P〈0.05） for liver or spleen of mice of 3 weeks old, distinct significant differences （P〈0.01） for liver or spleen and significant differences （P〈0.05） for bladder of mice of 5 weeks old; distinct significant differences （P〈0.01） for lungs or double kidneys and significant differences （P〈0.05） for spleen or bladder of mice of 7 weeks old were observed in the study. Conclusion： As the growth of Balb/c mice, the difference of organs between female and male mice is increasingly notable.