Effects of 2,4-dichlorophenoxyacetic acid on haematological indices in West African dwarf goats |
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| Institution: | 1. Department of Veterinary Physiology and Pharmacology, University of Nigeria, Nsukka, Nigeria;2. Department of Veterinary Pathology and Microbiology, University of Nigeria, Nsukka, Nigeria;3. Department of Veterinary Obstetrics and Reproductive Diseases, University of Nigeria, Nsukka, Nigeria;1. Department of Physics and Materials Science, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, China;2. School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, China;1. School of Energy Science and Engineering, University of Electronic Science and Technology of China (UESTC), Chengdu, People’s Republic of China;2. Institute of Microelectronics, Tsinghua National Laboratory for Information Science and Technology, Tsinghua University, Beijing, People’s Republic of China |
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| Abstract: | We investigated the possible toxicity of 2,4-dichlorophenoxyacetic acid (2,4-D) in West African dwarf goats. The goats (20) were randomly divided into four equal groups; three of which were exposed to graded levels (low, medium and high doses) of 2,4-D for a period of 6 weeks. Blood samples were collected from the treatment group goats as well as the control group goats on weeks 0, 2, 4 and 6. The blood samples were used for analysis of haematologic indices such as packed cell volume (PCV), erythrocyte count (EC), total leucocyte count (TLC), haemoglobin concentration (Hb), mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH) and mean corpuscular haemoglobin concentration (MCHC). Total leucocyte counts were significantly reduced (p < 0.05) by the test herbicide (2,4-D) in all the treatment groups. Significant reduction in the levels of PCV, Hb concentration, MCV, MCH and MCHC were also recorded in all treatment groups. There was no significant change (p > 0.05) in the erythrocyte count value of all the four groups. The significant reduction in the haematologic indices of West African dwarf goats (WADG) as evidenced from the result of this study, suggest the possibility of 2,4-D toxicity in these goats. |
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