Solid-phase synthesis of cyclic alkoxyketones, inhibitors of the cysteine protease cathepsin K |
| |
| Authors: | Fenwick A E Garnier B Gribble A D Ife R J Rawlings A D Witherington J |
| |
| Affiliation: | Department of Medicinal Chemistry, Smith Kline Beecham Pharmaceuticals, Essex, UK. |
| |
| Abstract: | Using solid-phase synthesis, a library of novel cyclic alkoxyketones has been constructed which show strong inhibitory activity against the cysteine protease, cathepsin K (EC 3.4.22.38). |
| |
| Keywords: | |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ |
|
