Detecting infiltrating lobular carcinoma using scintimammographic breast specific gamma imaging |
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| Affiliation: | 1. Department of Radiology, Hospital Sirio Libanes, São Paulo, SP, Brazil;2. Department of Radiology and Molecular Imaging, University of Alabama at Birmingham, Birmingham, AL, United States;3. Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States;4. Department of Oncology, Hospital Sirio Libanes, São Paulo, SP, Brazil;5. Department of Radiology and Diagnostic Imaging, Hospital Israelita Albert Einstein, São Paulo, SP, Brazil;6. Institute of Radiology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil;1. Department of Hematology and Bone Marrow Transplantation, Rambam Health Care Campus, Haifa, Israel;2. Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel |
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| Abstract: | This study evaluated the effectiveness of scintimammography performed with gamma cameras optimized for breast imaging in the detection of infiltrating lobular carcinoma. This new procedure, Breast Specific Gamma Imaging (BSGI), was conducted on 105 patient presenting with 113 breast lesions. Studies were conducted at two medical centers using three prototype cameras [14, 16]. Biopsy and pathology reports were obtained for all cases and, of the 34 detected carcinomas, 6 were determined to be infiltrating lobular type without mixed component other than lobular carcinoma in situ. Of the 6 lesions, 4 were smaller than 1 cm, the smallest moasuring 3 mm at biopsy. BSGI detected all 6 of the lobular carcinomas and correctly identified the secondary lesion in the only multifocal case. The BSGI foci sizes matched the lesion size at biopsy to within +/-5.5 mm, with about an equal number of cases ovar and under estimated. Conclusion: BSGI provides an effective tool for the detection of lobular carcinoma and in the determination of lesion size and multifocality. |
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