IL-17 family member cytokines: regulation and function in innate immunity |
| |
Authors: | Reynolds Joseph M Angkasekwinai Pornpimon Dong Chen |
| |
Institution: | Department of Immunology and Center for Inflammation and Cancer, M.D. Anderson Cancer Center, Houston, TX 77054, USA. |
| |
Abstract: | Recently, the IL-17 family member cytokines have become prominent subjects of investigation. IL-17 (IL-17A) is the best-described member of this family where its production has been mainly attributed to a specialized T helper subset of the adaptive immune response termed Th17. However, recent research on this and other Th17 cytokines has revealed new sources and functions of IL-17 family members in the innate immune response. This review will highlight recent advances in the field of IL-17 family member cytokines and will predominantly focus on the innate regulation and function of IL-17, IL-17F, and IL-25. |
| |
Keywords: | |
本文献已被 ScienceDirect PubMed 等数据库收录! |
|