微血管减压与经皮穿刺球囊压迫治疗原发性三叉神经痛的临床观察

目的:对比微血管减压(MVD)和经皮穿刺球囊压迫(PBC)治疗原发性三叉神经痛(PTN)的疗效。方法:选择2010年5月至2013年11月在我院接受治疗的PTN患者124例进行研究,根据数字法随机分成MVD组及PBC组各62例,两组分别行对应手术,随访18个月,对比两组手术相关指标、疗效以及术后并发症。结果:MVD组的手术时间与术中出血量,以及住院时间和住院费用均分别大于PBC组(均P0.05)。MVD组治疗后完全无痛的比例显著高于PBC组,轻度复发的比例显著低于PBC组(均P0.05)。MVD组的麻木及总并发症发生率均分别显著低于PBC组(均P0.05)。结论:MVD术式与PBC术式在治疗PTN时均具有较好的疗效,MVD术后无痛和并发症情况较好,而PBC创伤较小,较适合高龄体弱而无法耐受较大手术者,临床治疗时应合理地选用相关术式。

Effect Observation of Microvascular Decompression and Percutaneous Balloon Compression in the Treatment of Primary Trigeminal Neuralgia

Objective:To compare the effect of microvascular decompression(MVD) and percutaneous balloon compression(PBC) in the treatment of primary trigeminal neuralgia (PTN).Methods:124 patients with PTN were selected in our hospital from May 2010 to November 2013,who were divided into MVD group and PBC group according to the random number table method, with 62 patients in each group, and were respectively underwent the corresponding operation, followed up for 18 months, then compared the operation related indexes, effect and postoperative complications in two groups.Results:The operation time, blood loss, hospitalization time and cost in MVD group were greater than PBC group(P<0.05). Completely painless ratio in MVD group after treatment was significantly higher than PBC group, but the mild recurrence ratio was significantly lower than PBC group (P<0.05). The incidence of numbness and total complications in MVD group were significantly lower than PBC group (P<0.05).Conclusion:Both MVD and PBC has good effect in the treatment of PTN, completely painless ratio and complications of MVD are better, while the PBC is less invasive, which is more suitable for the frail elderly who is unable to tolerate the big operation, so they should be reasonably selected for clinical treatment.