内镜下喷洒蛇毒血凝酶与金属钛夹治疗不明原因消化道出血的临床疗效比较

目的:探讨内镜下喷洒蛇毒血凝酶与金属钛夹治疗不明原因消化道出血的临床疗效。方法:选取2013年8月至2015年12月本院收治的不明原因消化道出血患者82例,随机分为对照组和实验组,每组41例。对照组给予内镜下喷洒蛇毒血凝酶治疗,实验组给予金属钛夹止血治疗。观察两组患者经止血治疗后即时止血时间、外科手术率、输血量、症状消失时间和临床疗效、再出血率和出血量。结果:实验组即时止血率明显高于对照组,输血量低于对照组(P0.05);实验组呕血消失时间、潜血转阴时间和引流液变清时间均小于对照组(P0.05);实验组痊愈率、总有效率高于对照组(P0.05);两组之间再出血率和出血量比较差异无统计学意义(P0.05)。结论:金属钛夹较内镜下喷洒蛇毒血凝酶对不明原因消化道出血具有更好的临床疗效,且再出血率较低。

Comparison of the Clinical Efficacy of Endoscopic Spray Snake VenomandMetal TitaniumClip in the Treatment of Obscure Gastrointestinal Bleeding

Objective:To investigate the clinical efficacy of endoscopic spray snake venom and metal titanium clip in thetreatment of obscure gastrointestinal bleeding.Methods:82 patients with obscure gastrointestinal bleeding from August 2013 toDecember 2015 in our hospital were collected and randomly divided into the control group and the experimental group with 41 cases ineach group. Patients in the control group were treated by endoscopic spray snake venom treatment; while patients in the experimentgroup were treated by metal titanium clip hemostatic treatment. The hemostatic instant hemostatic time, rate of surgery, blood transfusionamount, symptoms disappeared time and clinical efficacy were observed between two groups.Results:After treatment by the secondsolution, the instant hemostasis rate of experimental group was significant higher than that of the control group, the blood transfusionamount was lower than that of the control group (P < 0.05); the hematemesis disappeared time, occult blood clearance time and drainageliquid cleared time of the experimental group were less than those of the control group (P < 0.05); the cure rate and total effective rate ofthe experimental group were higher than those of the control group (P<0.05). No statistically significant difference was found in thebleeding rate and bleeding amount between two groups (P>0.05).Conclusion:Metal titanium clip had better clinical efficacy and lowerbleeding rate than endoscopic spray snake venomin the treatment of obscure gastrointestinal bleeding.