冠心病患者的血脂、胆红素、UA及Fib水平变化及临床意义

目的:研究冠心病(CHD)患者的血脂、胆红素、血尿酸(UA)及纤维蛋白原(Fib)水平变化及临床意义。方法:选取2014年4月到2015年4月我院收治的CHD患者110例(研究组),另选取同期健康体检者110例(对照组),检测两组受检者血清总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、直接胆红素(DBIL)、间接胆红素(IBIL)、总胆固醇(TBIL)、UA以及Fib水平。结果:研究组TC、TG、LDL-C、UA以及Fib水平均显著高于对照组,两组比较差异具有统计学意义(P0.05);研究组HDL-C、DBIL、IBIL以及TBIL均显著低于对照组,两组比较差异具有统计学意义(P0.05)。结论:血脂水平异常,胆红素水平降低,UA以及Fib水平增高与CHD的发病有关。

Changes of SerumLipids, Bilirubin, UA and Fib Levels in Patients with Coronary Heart Disease

Objective:To study the changes and clinical significance of serumlipids, bilirubin, uric acid (UA) and fibrinogen(Fib) levels in patients with coronary heart disease (CHD).Methods:A total of 110 patients with CHD, who were admitted to Fuzhou Chinese Medicine Hospital from April 2014 to April 2015, were chosen as study group, and 110 healthy people in the same period, as control group. The total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), direct bilirubin(DBIL), indirect bilirubin (IBIL), total cholesterol(TBIL), UA and Fib levels of the two groups were detected.Results:TC, TG, LDL-C, UA and Fib levels in the study group were significantly higher than those in the control group, the differences were statistically significant(P<0.05). HDL-C, DBIL, IBIL and TBIL in the study group were significantly lower than those in the control group, the differences were statistically significant (P<0.05).Conclusion:Abnormal serumlipids, bilirubin reducing, UA and Fib increasing are related with the development of CHD.