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保乳手术和改良根治手术在乳腺癌患者临床治疗的效果研究
引用本文:王妍 原晓燕 邱衍哲 尚永健 张晓元 张春侠. 保乳手术和改良根治手术在乳腺癌患者临床治疗的效果研究[J]. 现代生物医学进展, 2016, 16(24): 4759-4762
作者姓名:王妍 原晓燕 邱衍哲 尚永健 张晓元 张春侠
作者单位:空军航空医学研究所附属医院普外科;解放军总医院乳腺外科
基金项目:北京市科技计划首都临床特色应用研究专项(Z131100004013091)
摘    要:目的:通过对比乳腺癌手术分别采用保乳手术和改良根治手术的治疗效果,探讨分析两种不同的手术方法的疗效差异,为临床治疗和相关研究提供参考。方法:选取88例乳腺癌患者作为研究对象,并以不同的临床手术治疗方法为依据,将两组患者分为研究组和对照组,各44例,就诊时间为2010年2月至2011年12月。研究组给予保乳手术,对照组给予改良根治手术。对两组患者的手术时间、住院时间、术中出血量、并发症发生率以及两组患者的躯体评分、心理评分、社会评分和精神评分等各项生存质量评分结果为观察指标。结果:研究组患者的手术时间小于对照组,研究组患者的住院时间短于对照组,研究组患者的并发症发生率低于对照组,研究组的术中出血量少于对照组,差异有统计学意义(P0.05);研究组患者的躯体评分、心理评分、社会评分和精神评分等各项生存质量评分结果均高于对照组,差异均有统计学意义(P0.05)。结论:与改良根治手术相比较,采用保乳手术治疗乳腺癌的临床综合效果显著,患者的术后生活质量更好,是临床治疗乳腺癌的理想选择方式之一。

关 键 词:保乳手术;改良根治手术;乳腺癌

The Study of the Effect of Breast-conserving Surgery and Modified RadicalSurgery in the Clinical Treatment of Breast Cancer Patients
Abstract:Objective:To investigate the clinical effect of breast-conserving surgery and modified radical surgery on the treatmentof breast cancer, so as to provide a reference for clinical diagnosis and treatment.Methods:88 cases with breast cancer who were treatedin our hospital fromFebruary 2010 to December 2011 were chosen as the research objects. According to the different treatment methods,the patients were divided into the study group and the control group, with 44 patients in each group. The patients in the study group weretreated with the breast-conserving surgery, while the patients in the control group were treated with the modified radical surgery. Then theoperation time, the hospitalization, the blood loss, the complications, and physical and psychological scores, and social and spiritualstages were observed and compared between the two groups before and after the treatment.Results:The operation time in the studygroup was shorter than that of the control group, and the hospitalization in the study group was shorter than that of the control group, theblood loss in the study group was less than that of the control group, the incidence of complications in the study group was lower thanthat of the control group, and the differences were statistically significant (P<0.05). The physical score, score psychological, social andspiritual score ratings and other quality of life scores in the study group were higher than that the control group, and the differences werestatistically significant (P<0.05).Conclusion:Compared with modified radical surgery, the clinical effect of breast-conserving surgery forbreast cancer is more significant, the postoperative quality of life of patients is better, and it is one of the ideal ways for the clinicaltreatment of breast cancer.
Keywords:Breast-conserving surgery   Modified radical surgery   Breast cancer
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