呼吸机相关性肺炎的常见病原菌耐药性分析 |
| |
引用本文: | 林洁,孔晋亮,黄天霞,刘凤鸣,于虹.呼吸机相关性肺炎的常见病原菌耐药性分析[J].现代生物医学进展,2016,16(21):4075-4078. |
| |
作者姓名: | 林洁 孔晋亮 黄天霞 刘凤鸣 于虹 |
| |
作者单位: | 广西南宁市第一人民医院呼吸内科;广西医科大学第一附属医院呼吸内科;广西南宁市第一人民医院重症医学科 |
| |
基金项目: | 广西壮族自治区卫生厅资助项目(Z2014479) |
| |
摘 要: | 目的:探讨呼吸机相关性肺炎(VAP)的常见病原菌并分析其耐药性,为临床治疗提供依据。方法:选取我院收治的135例VAP患者的临床资料,分析其病原菌分布以及抗菌药物的耐药性。结果:135例患者中共分离出183株病原菌,其中革兰氏阴性菌135株(占73.77%),革兰氏阳性细菌33株(占18.03%),真菌15株(占8.20%)。革兰氏阴性菌主要为鲍曼不动杆菌,占35.52%,革兰氏阳性细菌主要为金黄色葡萄球菌,占9.84%,革兰阳性菌无一对万古霉素耐药,除了米诺环素总耐药率为42.42%外,其余病原菌对于常用的药物总耐药率均大于60.0%,革兰阴性菌普遍存在多药耐药现象。结论:引起VAP患者感染的主要致病菌为革兰阴性菌群,且存在严重的多重耐药现象,在临床上应加强对VAP疾病的预防和控制,合理应用抗菌药物。
|
关 键 词: | 呼吸机相关性肺炎 病原菌 耐药性 |
Analysis on the Common Pathogenic Bacteria of Ventilator Associated
Pneumonia and the Drug Resistance* |
| |
Abstract: | Objective:To study the common pathogenic bacteria of ventilator associated pneumonia (VAP) and to analyze its drug
resistance, so as to provide data for clinical treatment.Methods:The clinical data of 135 patients with VAP in our hospital were retrospectively
analyzed. Their pathogenic bacteria distribution and antimicrobial resistance were investigated.Results:Totally, 183 strains of
pathogenic bacteria was isolated from 135 patients. Of them, there were 135 strains (73.77%) of gram-negative bacteria, 33 (18.03%)
strains of grampositive bacteria, 15 strains (8.20%) of fungi. Gram-negative bacteria mainly included (35.52%).
And gram-positive bacteria mainly included (9.84%). There was no vancomycin resistance among gram positive
bacteria. Except the total resistance percentage to minocycline was 42.42%, the total resistance to commonly drugs in rest of the
pathogenic bacteria all were greater than 60.0%. Gram-negative bacteria had a widespread multi-resistant phenomenon.Conclusion:The
main pathogenic bacteria causing infections in VAP patients were gram-negative bacteria, and there were serious multi-drug resistance
phenomenon. We should strengthen the prevention and control of VAP and make reasonable use of the antimicrobial agents. |
| |
Keywords: | Ventilator associated pneumonia Pathogenic bacteria Drug resistance |
本文献已被 CNKI 等数据库收录! |
| 点击此处可从《现代生物医学进展》浏览原始摘要信息 |
|
点击此处可从《现代生物医学进展》下载全文 |
|