Synapses let loose for a change: inhibitory synapse pruning throughout experience-dependent cortical plasticity |
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| Authors: | Gambino Frédéric Holtmaat Anthony |
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| Affiliation: | Department of Basic Neurosciences, Faculty of Medicine, University of Geneva, Geneva, Switzerland. |
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| Abstract: | In this issue of Neuron, Chen et?al. (2012) and van Versendaal et?al. (2012) used fluorescently tagged gephyrin to track inhibitory synapses in the mouse visual cortex in?vivo. Their studies show that visual experience-dependent plasticity is associated with clustered and location-specific pruning of inhibitory synapses. |
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