Structure and antibacterial activity of the silver(I) complex of 2-aminophenoxazine-3-one |
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| Authors: | Pandurangan Komala Gallagher Shane Morgan Grace G Müller-Bunz Helge Paradisi Francesca |
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| Affiliation: | Centre for Synthesis and Chemical Biology, School of Chemistry and Chemical Biology, University College Dublin, Belfield, Dublin 4, Ireland. |
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| Abstract: | The crystal structure and antibacterial activity of the first metal complex of 2-aminophenoxazine-3-one is reported. We describe the silver(i) complex of this important biological molecule and show that the binding mode is through the phenoxazine ring nitrogen. A new synthetic route to 2-aminophenoxazine-3-one is also reported. |
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