Interaction of cytochrome P-450scc with cytochrome b5 |
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Authors: | S A Usanov V L Chashchin |
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Affiliation: | Institute of Bioorganic Chemistry, BSSR Academy of Sciences, Minsk, USSR. |
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Abstract: | Spectrophotometric, affinity chromatography and cross-linking experiments provided evidence that cytochrome P-450scc from bovine adrenocortical mitochondria forms a tight complex with cytochrome b5 from rabbit liver microsomes. In the reconstituted system cholesterol side chain activity of cytochrome P-450scc was enhanced by the addition of cytochrome b5. |
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