Microbial kinetic resolution of 2-substituted-1-propanol |
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| Authors: | K Miyamoto K Fujimori J-I Hirano |
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| Institution: | Department of Biosciences and Informatics, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama, Japan |
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| Abstract: | Micro-organisms that assimilate 2-phenylethanol were screened from soil and strains that enantioselectively oxidized 2-phenyl-1-propanol to 2-phenylpropanoic acid were selected. By optimizing the cultural conditions as well as the reaction conditions, various enantiomerically enriched 2-substituted propanoic acids and 2-aryl-1-propanols were obtained. |
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| Keywords: | Enzymatic oxidation kinetic resolution 2-substituted-1-propanol screening |
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