Synthesis of FF8181-A |
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Authors: | Kobayashi Noriaki Kuniyoshi Hidenobu Ishigami Ken Watanabe Hidenori |
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Affiliation: | Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan. |
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Abstract: | Both enantiomers of FF8181-A were synthesized through optical resolution from the known Diels-Alder reaction product in 15 steps. The absolute configuration of the natural product was determined to be 1S,5S,5aS,9aS,9bS. |
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