Inhibition of colicin e2 activity by bacterial lipopolysaccharide |
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| Authors: | Chang Y Y Hager L P |
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| Affiliation: | Department of Biochemistry, University of Illinois, Urbana, Illinois 61801. |
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| Abstract: | Lipopolysaccharide isolated from colicin E2-sensitive Escherichia coli and from “receptor-minus” mutants inhibits the activity of colicin E2. Lipid A and the polysaccharide fraction obtained by mild acid hydrolysis of lipopolysaccharide are inactive either alone or when tested in combination. Periodate oxidation of lipopolysaccharide destroys over 85% of its inhibition activity. |
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