Development of a novel neodymium compound for in vivo fluorescence imaging. |
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Authors: | Kazuki Aita Takashi Temma Yuji Kuge Hideo Saji |
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Affiliation: | Department of Patho-functional Bioanalysis, Graduate School of Pharmaceutical Sciences, Kyoto University, Japan. |
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Abstract: | We developed a novel fluorescent probe that contains the neodymium(III) complex moiety and fluorescein moiety. This probe can emit long-lived near-infrared luminescence derived from a Nd ion through excitation of the fluorescein moiety with visible light (lambda(ex) = 488 nm, lambda(em) = 880 nm, lifetime = 2.3 micros). These results indicate the possibility of the probe as a candidate for in vivo fluorescence molecular imaging. |
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Keywords: | neodymium near‐infrared fluorescein energy transfer long‐lived luminescence |
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