Receptors to Dolichos biflorus Agglutinin |
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Authors: | H FUJIMOTO TAKASHI MURAMATSU HIDEKO URUSHIHARA K O YANAGISAWA |
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Institution: | Department of Cell Biology, Mitsubishi-Kasei Institute of Life Sciences, 11 Minamiooya, Machida-shi, Tokyo 194, Japan;Department of Biochemistry, Kagoshima University School of Medicine, Usuki-cho, Kagoshima 890, Japan |
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Abstract: | Dolichos biflorus agglutinin (DBA), a lectin specific to N-acetylgalactosamine residue, identifies cell surface markers on teratocarcinoma cells. These receptors are found in very limited types of adult tissues. In the present investigation, mouse embryos collected on days 1 (2-cell) to 3 (early blastocyst) were shown to be stained with FITC-conjugated DBA. Embryos homozygous for t w32 were also positively stained. These results suggest that receptors for DBA on preimplantation embryos include components distinct from Forssman, F9, and SSEA-1 antigens. |
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