| Genetic variation between Helicobacter pylori strains: gene acquisition or loss? |
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| 引用本文： | Garcia-Vallvé S,Janssen PJ,Ouzounis CA. Genetic variation between Helicobacter pylori strains: gene acquisition or loss?[J]. Trends in microbiology, 2002, 10(10): 445-447. DOI: 10.1016/S0966-842X(02)02446-0 |
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| 作者姓名： | Garcia-Vallvé S Janssen PJ Ouzounis CA |
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| 摘 要： |
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Genetic variation between Helicobacter pylori strains: gene acquisition or loss? |
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| Garcia-Vallvé Santiago,Janssen Paul J,Ouzounis Christos A. Genetic variation between Helicobacter pylori strains: gene acquisition or loss?[J]. Trends in microbiology, 2002, 10(10): 445-447. DOI: 10.1016/S0966-842X(02)02446-0 |
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| Authors: | Garcia-Vallvé Santiago Janssen Paul J Ouzounis Christos A |
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| Affiliation: | Departament de Bioquimica i Biotecnologia, Universitat Rovira i Virgili, Pl Imperial Tarraco 1, Tarragona, Spain. vallve@quimica.urv.es |
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| Abstract: | Previously identified strain-specific genes of Helicobacter pylori were analysed for GC content and preference in codon usage. The results indicate that in H. pylori strain specificity is mainly driven by gene uptake. Incoming strains of Helicobacter or other species can occasionally donate genes but the identification of the donor species is hampered by ongoing evolutionary processes and the lack of an adequate number, or indeed a total absence, of gene homologues. |
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