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Activation of TM7SF2 promoter by SREBP-2 depends on a new sterol regulatory element,a GC-box,and an inverted CCAAT-box |
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| Authors: | Gianluca Schiavoni Anna Maria Bennati Marilena Castelli Maria Agnese Della Fazia Tommaso Beccari Giuseppe Servillo Rita Roberti |
| Institution: | 1. Department of Internal Medicine, Laboratory of Biochemistry, University of Perugia, via del Giochetto, 06122 Perugia, Italy;2. Department of Clinical and Experimental Medicine, University of Perugia, Italy;3. Department of SEEA, University of Perugia, Italy |
| Abstract: | |
| Keywords: | SRE sterol regulatory element SREBP-2 SRE-binding protein 2 NF-Y nuclear factor Y LDLR low density lipoprotein receptor FBS foetal bovine serum Lov lovastatin 25-OH chol 25-hydroxycholesterol LPDS lipoprotein deficient serum EMSA electrophoretic mobility shift assay ChIP chromatin immunoprecipitation |
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