|
|||||
|
|
Kinetic study of acid-soluble DNA formation under the effect of DNase I |
|
| Authors: | T M Fedorova V P Miakisheva S P Grabarev L N Ryskukova |
| Abstract: | A mathematical model of acid-soluble DNA formation under the effect of DNase I was developed. The data from the kinetic analysis suggest that at the stage of 10-60% solubilization the number of breaks in DNA single strands seem to be linearly dependent on the increment of acid-soluble DNA. This stage of acid-soluble DNA formation may be interpreted in terms of the monomolecular (pseudomonomolecular) reaction. |
| Keywords: | |