In vivo antitumor activity of chitosan nanoparticles |
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Authors: | Qi Lifeng Xu Zirong |
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Affiliation: | Zhejiang University, Nano-Biology Lab of Animal Science College, Hangzhou, PR China. lifengq01@hotmail.com |
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Abstract: | Chitosan nanoparticles have been synthesized as potential anticancer agents, and evaluated, in vitro, against various cancer cell lines. In this study, in vivo antitumor activity of chitosan nanoparticles against Sarcoma-180 and mouse hepatoma H22 was investigated. Chitosan nanoparticles showed significant antitumor activity in vivo. The doses and particle size made a great effect on their efficacy. |
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