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Plasminogen Activators in Vascular Remodeling and Angiogenesis
Authors:Ye V Parfyonova  O S Plekhanova  V A Tkachuk
Institution:(1) Russian Cardiology Research Center, Ministry of Health of the Russian Federation, 3-ya Cherepkovskaya ul. 15a, Moscow, 121552, Russia
Abstract:This review considers cellular and molecular mechanisms of the involvement of plasminogen activators in extracellular proteolysis and cell migration and proliferation. The role of plasminogen activators in vascular remodeling in atherosclerosis, restenosis, and angiogenesis is discussed.
Keywords:urokinase  tissue plasminogen activator  cell migration  vascular remodeling  restenosis  angiogenesis
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