Restriction endonuclease resistant chromatin in human chromosomes |
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| Authors: | Arvind Babu and Ram S Verma |
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| Institution: | (1) Division of Genetics, Beth Israel Medical Center, Mount Sinai Medical Center, New York, New York, USA;(2) Division of Genetics, Long Island College Hospital, State University of New York, Health Science Center Brooklyn, 340 Henry Street, 11201, NY, USA |
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| Abstract: | Summary The recent addition of restriction endonucleases in obtaining selective bands in the human genome has added a new dimension to molecular genetics. However, a considerable discrepancy exists in banding patterns produced by AluI in chromosomes 19 and 20, by MboI in chromosomes 4, 5, 8, 21 and 22 and by RsaI in chromosomes 12, 21 and 22. The principal causes of these differences are highlighted. |
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| Keywords: | Restriction enzymes Resistant chromatin Chromosome |
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