Effect of copper coordination complexes on sister-chromatid exchanges in plant cells |
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| Authors: | M J Hazen A Juarranz J C Stockert A González D Beltrán-Porter |
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| Institution: | Departamento de Biología, Facultad de Ciencias, Universidad Autónoma de Madrid, Spain. |
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| Abstract: | The effectiveness of several copper coordination complexes in the induction of sister-chromatid exchanges (SCE) in meristematic cells of Allium cepa roots was studied. A significant increase in the frequencies of SCE was observed when cells were exposed to different concentrations of copper complexes for 3 h. This effect, which is concentration dependent, seems to be related to the possibility of intercalative binding modes between the planar copper complexes and DNA. |
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