(1) Department of Computing, City University, London, EC1V 0HB, UK;(2) Dunn Human Nutrition Unit, Medical Research Council, Cambridge, CB2 2XY, UK;(3) Department of BioSystems, Korea Advanced Institute of Science and Technology, Korea
Abstract:
Background
Large-scale protein interaction maps provide a new, global perspective with which to analyse protein function. PSIMAP, the Protein Structural Interactome Map, is a database of all the structurally observed interactions between superfamilies of protein domains with known three-dimensional structure in the PDB. PSIMAP incorporates both functional and evolutionary information into a single network.
