Impact de la tomographie par émission de positons au 18fluorodésoxyglucose dans la prise en charge des cancers de primitif inconnu |
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| Institution: | 1. The University of Chicago Medicine, Section of Gynecologic Oncology, Department of Obstetrics and Gynecology, 5841 S. Maryland Avenue, MC 2050, Chicago, IL 60637, United States;2. The University of Chicago Medicine, Department of Radiology, 5841 S. Maryland Avenue, MC 2026, Chicago, IL 60637, United States;3. The University of Chicago, Department of Public Health Sciences, 5841 S. Maryland Avenue, MC 2000, Chicago, IL 60637, United States;1. Feinberg School of Medicine, Northwestern University, Chicago, Illinois;2. Division of Plastic and Reconstructive Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois;3. Lynn Sage Comprehensive Breast Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois;4. Department of Radiation Oncology, The Robert H. Lurie Comprehensive Cancer Center, Chicago, Illinois |
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| Abstract: | Aim and methodThis retrospective study, performed on 37 patients, gave us the opportunity to evaluate the impact of 18F-FDG PET/CT for cancer of unknown primary (CUP). We first wanted to study the precision of the exam to detect the primary, after a negative check-up, for the extension of the disease, and to judge the impact of the results on management and survival of those patients.ResultThe PET/CT led to the detection of the primary for 14 patients out of 37, after a negative check-up composed of five exams on average. For 10 patients, the exam allows the detection of supplementary metastases. The management was changed after the exam in more than one third of the patients, but without any significant impact on the time of survival of these patients, for whom the prognostic is usually dismal.ConclusionThe 18F-FDG PET/CT appears a valuable tool for detection of primary, changing the management of many of the patients. These results must be completed by a prospective study, in particular to judge the impact of exam's results on the survival. |
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