The oculomotor periphery: the clinician's focus is no longer a basic science stepchild |
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| Authors: | John D Porter Paraskevi Karathanasis Philip H Bonner Jennifer K Brueckner |
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| Institution: | aDepartment of Anatomy and Neurobiology, University of Kentucky, Lexington, Kentucky 40536-0084, USA;bDepartment of Ophthalmology, University of Kentucky, Lexington, Kentucky 40536-0084, USA;cSchool of Biological Sciences, University of Kentucky, Lexington, Kentucky 40536-0084, USA |
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| Abstract: | The study of the oculomotor periphery, the extraocular muscles and their orbital attachments, is undergoing a rapid expansion. This is an important progression for both basic and clinical communities as, for too long, the ophthalmologist has worked primarily in the periphery and the basic researcher has been occupied with study of the central components of the oculomotor system. From recent studies, it is clear that the morphology, cell and molecular biology, and genetics of the eye muscles and their corresponding motoneuron pools, and muscle attachments within the orbit are more complex than has heretofore been appreciated. |
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| Keywords: | Abbreviations: AChR acetylcholine receptor CFEOM congenital fibrosis of the EOMs EOM extraocular muscle MG myasthenia gravis MRI magnetic resonance imaging mtDNA mitochondrial DNA |
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