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关节镜制备膝关节软骨缺损的动物模型
引用本文:左镇华,杨柳,段小军,王富友. 关节镜制备膝关节软骨缺损的动物模型[J]. 现代生物医学进展, 2007, 7(11): 1665-1666,F0003
作者姓名:左镇华  杨柳  段小军  王富友
作者单位:第三军医大学西南医院关节外科中心,重庆,400038
基金项目:国家自然科学基金;军队医药卫生科研项目
摘    要:目的:经微创手术制备膝关节软骨缺损动物模型,减少因手术创伤造成对实验结果的影响。方法:关节镜下对9只山羊(9膝)进行关节面钻孔术,造成软骨缺损模型,对其缺损位置进行准确定位。结果:9只山羊(9膝)均在关节镜下顺利进行了关节软骨缺损模型的建立,并进行了缺损部位的定位。结论:对比开放性手术,经关节镜制备关节缺损模型是一种对实验干预最少的微创方法,有助于减少手术本身造成的实验误差。

关 键 词:关节镜  山羊  膝关节  软骨缺损  动物模型
文章编号:1673-6273(2007)11-1665-02
修稿时间:2007-09-132007-09-28

Preparation of an Animal Model of Articular Cartilage Defect in the Knee of Goat by Arthroscopy
ZUO Zhen-hua,YANG Liu,DUAN Xiao-jun,WANG Fu-you. Preparation of an Animal Model of Articular Cartilage Defect in the Knee of Goat by Arthroscopy[J]. Progress in Modern Biomedicine, 2007, 7(11): 1665-1666,F0003
Authors:ZUO Zhen-hua  YANG Liu  DUAN Xiao-jun  WANG Fu-you
Affiliation:Center For Joint surgery, Southweast Hospital, Third Military Medical University, Chongqing 400038, China
Abstract:Objective:To construct animal models of articular cartilage lesions in the knee of goats by arthroscopy to minimize the surgical injury.Methods:Subchondral drilling to create the chondral defect on articular cartilage were performed on 9 goats(9 joints) by arthroscope.Results:The chondral defect models were successefully constructed on 9 goats(9 joints)and accurately located by arthroscopy.Conclusion:Preparing animal models of chondral defects by arthroscopy result in fewer injuries and experimental errors as compared with open surgery.
Keywords:Goat  Arthroscope chondral defect  Animal model
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