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A tandem laboratory scale protein purification process using Protein A affinity and anion exchange chromatography operated in a weak partitioning mode |
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| Authors: | Michael Shamashkin Ranga Godavarti Timothy Iskra Jon Coffman |
| Affiliation: | 1. +1‐617‐274‐3279+1‐617‐274‐3246;2. Centers for Therapeutic Innovation, Pfizer, Inc., , Boston, Massachusetts, 02115;3. Pfizer Global Biologics, Pfizer, Inc., , Andover, Massachusetts;4. Boehringer Ingelheim Fremont, Inc., , Fremont, California |
| Abstract: | |
| Keywords: | weak partitioning chromatography anion exchange chromatography tandem purification integrated continuous bioprocessing multidimensional preparative chromatography |