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Non‐invasive UPR monitoring system and its applications in CHO production cultures
Authors:Zhimei Du  David Treiber  Rebecca E McCoy  Amanda K Miller  Mei Han  Feng He  Sarah Domnitz  Carole Heath  Pranhitha Reddy
Institution:1. Department of Cell Sciences and Technology, Amgen, Inc., 1201 Amgen Court West, Seattle, Washington 98119;2. telephone: 206‐265‐7367;3. 206‐217‐4692;4. Department of Drug Product Development, Amgen, Inc., Seattle, Washington;5. Department of Biologics Optimization, Amgen, Inc., Seattle, Washington
Abstract:
Keywords:production process  cell line development  cell culture  ER stress
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