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Fast and scalable purification of a therapeutic full‐length antibody based on process crystallization |
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| Authors: | Benjamin Smejkal Neeraj J. Agrawal Bernhard Helk Henk Schulz Marion Giffard Matthias Mechelke Franziska Ortner Philipp Heckmeier Bernhardt L. Trout Dariusch Hekmat |
| Affiliation: | 1. Institute of Biochemical Engineering, Technische Universit?t München, , 85748 Garching, Germany;2. Chemical Engineering, Massachusetts Institute of Technology, , Cambridge, Massachusetts;3. Novartis Pharma AG, , Basel, Switzerland |
| Abstract: | |
| Keywords: | therapeutic monoclonal antibody purification process stirred process crystallization scale‐up CHO cell culture harvest alternative to chromatography |