Algicidal diterpenes from the brown alga Dictyota dichotoma

Bioassay-guided fractionation of an ethanol extract of the brown alga, Dictyota dichotoma, led to the isolation of a novel chlorine-containing perhydroazulene diterpene together with two known diterpenes, dictyolactone and sanadaol. The structure of the novel compound, named dictyol J, was elucidated on the basis of spectroscopic information. Dictyolactone showed the highest algicidal activity against red-tide phytoplanktons among the three isolated compounds.