Morphology,Solid Structure and Antioxidant Activity in Vitro of Angelica sinensis Polysaccharide-Ce(IV) |
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Authors: | Kaiwen Li Jie Wang Zizhen Huang Chunxia Tan |
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Institution: | Gansu University of Traditional Chinese Medicine, Lanzhou, 730000 China |
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Abstract: | Angelica Sinensis polysaccharide cerium (ASP?Ce) was prepared by Angelica Sinensis polysaccharide (ASP) and cerium ammonium nitrate (NH4)2Ce(NO3)6. and its morphology, and solid structure was investigated. The antioxidant activity of the ASP?Ce complex in vitro was evaluated. The antioxidant activity of ASP?Ce complex in vitro was evaluated by the scavenging activity of 2,2-diphenyl-1-picrylhyrazyl radical (DPPH), hydroxyl radical (?OH) and superoxide anion radical ( ?). The results showed that the ASP?Ce had the more ordered structure for inserting the Ce4+ into the polymer chain of ASP and there was little change in the conformation of the polysaccharide from Ce4+. Three free radical scavenging experiments proved that ASP?Ce had better antioxidant capacity than of ASP, especially on DPPH, and then on ?. The scavenging rate of ASP?Ce at 1.0 mg/mL on DPPH reached 71.6 %. Therefore, these results provide references for the further development and utilization of rare earth-polysaccharide. |
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Keywords: | ASP ASP?Ce morphology structure antioxidant activity |
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