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Two New C19-Diterpenoid Alkaloids from Delphinium shawurense |
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| Authors: | Nurfida Ablajan Wen-Juan Xue Jiang-Yu Zhao Abdubakiev Sardorbek Nurmirza Boymirzayevich Begmatov Shamansur Sagdullaev Bo Zhao Haji Akber Aisa |
| Affiliation: | 1. State Key Laboratory Basis of Xinjiang Indigenous Medicinal Plants Resource Utilization, Chinese Academy of Sciences, South Beijing Road 40–1, Urumqi, 830011 Xinjiang, P. R. China;2. State Key Laboratory Basis of Xinjiang Indigenous Medicinal Plants Resource Utilization, Chinese Academy of Sciences, South Beijing Road 40–1, Urumqi, 830011 Xinjiang, P. R. China S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, 100170 Tashkent, Uzbekistan;3. S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, 100170 Tashkent, Uzbekistan |
| Abstract: | Shawurenine C ( 1a ) and D ( 1b ), a new pair of regioisomeric C19-diterpenoid alkaloids, and five known C19-diterpenoid alkaloids ( 2 – 6 ) were isolated from the aerial part of Delphinium shawurense W. T. Wang. The chemical structures of new compounds were established based on spectroscopic analyses: HR-ESI-MS, and 1D, 2D NMR spectroscopic data. The anti-inflammatory and cytotoxic activities of these diterpenoid alkaloids were also evaluated. |
| Keywords: | Delphinium sharwurense C19-diterpenoid alkaloids shawurenine anti-inflammatory cytotoxic activity |