拉沙热研究进展

拉沙热(Lassa fever,LF)由拉沙病毒(Lassa virus,LASV)引起,是一种通过鼠类传播给人的急性出血性动物源性传染病,病死率高。主要在西非地区流行,但在全球多个国家发现输入性病例。本文主要针对拉沙病毒的病原学特点、疾病流行现状、临床特征、实验室检测、治疗及预防进展进行综述。同时,建议在全球经济一体化的大形势下,加强对拉沙热国际防控的关注度,建立国际联防联控防治策略和措施,并将其纳入全球防控体系。

Research progress on Lassa fever

Lassa fever (LF ) caused by Lassa virus (LASV ) is an acute hemorrhagic zoonotic disease transmitted to humans by rodent . The disease has high mortality , and mainly endemic in West Africa . However ,the imported cases have been reported in many countries worldwide .In this review ,we focus on the etiology of Lassa virus , disease prevalence , clinical features , laboratory testing , treatment and prevention .In light of the global economic integration , it is recommended that the strengthening of prevention and control of Lassa fever ,establishment of international strategies on prevention measures ,and integration into the global system should be paid more attention .