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Phosphorylation at Ser65 modulates ubiquitin conformational dynamics
Institution:1. Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, 725 N. Wolfe Street, WBSB 706, Baltimore, MD 21205, USA;2. Department of Physiology and Biophysics, University of California, Irvine, 825 Health Sciences Road, Irvine, CA 92697, USA;1. Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560 012, India;1. Structural Biology Laboratory, Council of Scientific and Industrial Research–Institute of Microbial Technology (CSIR-IMTECH), Chandigarh 160036, India;2. Infection and Immunology Group, Tuberculosis Research Laboratory, Translational Health Science and Technology Institute, NCR-Biotech Science Cluster, 3rd Milestone, Faridabad Gurugram Expressway, Faridabad-121001, India;1. Department of Pharmacology and Chemical Biology, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China;2. Research Centre for Marine Drugs, State Key Laboratory of Oncogene and Related Genes, Department of Pharmacy, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China;3. Institute of Marine Biomedicine, Shenzhen Polytechnic, Shenzhen 518055, China;4. Medicinal Bioinformatics Center, Shanghai JiaoTong University School of Medicine, Shanghai China;5. Key Laboratory of Medical Epigenetics and Metabolism, Institutes of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai 200032, China;1. Department of Emergency Medicine of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China;2. Department of Biophysics, and Department of Infectious Disease of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China;3. Zhejiang Provincial Key Laboratory of Immunity and Inflammatory Diseases, Hangzhou 310058, China;1. Faculty of Biochemistry and Molecular Medicine, University of Oulu, 90220 Oulu, Finland;2. CEITEC Masaryk University, Kamenice 5, 62500 Brno, Czech Republic;3. Molecular & Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences & Helsinki Institute of Life Science-Institute of Biotechnology, University of Helsinki, 00790 Helsinki, Finland;1. Systems Biology Ireland, School of Medicine, University College Dublin, Dublin 4, Ireland;2. UCD Charles Institute of Dermatology, School of Medicine, University College Dublin, Dublin 4, Ireland;3. Department of Molecular Medicine, University of Pavia, 27100 Pavia, Italy
Abstract:
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  • Keywords:ubiquitin  phosphorylation  molecular dynamics  string method
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