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Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response
Affiliation:1. Department of Biochemistry, Emory University School of Medicine, Atlanta, GA 30322, USA;2. ICGEB-Emory Vaccine Center, International Center for Genetic Engineering and Biotechnology, New Delhi 110067, India;3. Department of Pediatrics, Division of Infectious Diseases, Emory University School of Medicine, Emory University, Atlanta, GA 30322, USA;4. Department of Microbiology and Immunology, Emory University School of Medicine, Emory University, Atlanta, GA 30322, USA;5. Emory Vaccine Center, Emory University, Atlanta, GA 30322, USA;6. Kusuma School of Biological Sciences, Indian Institute of Technology, New Delhi 110016, India;7. Georgia Tech, Atlanta, GA 30332, USA;8. Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA;9. Department of Pathology, Brigham and Women’s Hospital, Boston, MA 02215, USA;10. Structural Parasitology Group, International Center for Genetic Engineering and Biotechnology, New Delhi 110067, India
Abstract:
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  • Keywords:COVID-19  SARS-CoV-2 variants  human monoclonal antibodies  cryo-EM structure  neutralizing antibodies  shared antibody response
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