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Effect of an extract of mouse Ehrlich ascitic tumor cells on mitotic activity and DNA synthesis in that tumor]
Authors:A I Antokhin  V P Barysheva  Iu A Romanov  V P Rybakov
Abstract:The extract of Ehrlich's ascitis tumour cells depressed specifically the proliferative activity of this tumour cells. This was expressed in a marked reduction in the number of dividing and DNA-synthesizing cells after the extract injection. The mitotic index fell considerably as soon as 2 hours after the injection, reached the minimum in 4 to 5 hours and was restored to the control level in 9 to 12 hours. The radioactive index appeared to be evenly decreased in the course of 18 hours of the experiment.
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