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Amplification of the gene for SCAP, coupled with Insig-1 deficiency, confers sterol resistance in mutant Chinese hamster ovary cells
Authors:Lee Peter C W  Liu Pingsheng  Li Wei-Ping  Debose-Boyd Russell A
Institution:Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390-9046, USA.
Abstract:
Keywords:cholesterol homeostasis  endoplasmic reticulum-Golgi translocation  ubiquitination  somatic cell genetics  mutagenesis  sterol-sensing domain  sterol-regulatory element binding protein cleavage-activating protein
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