Vgamma2Vdelta2+ T cells and anti-microbial immune responses |
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| Authors: | Chen Zheng W Letvin Norman L |
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| Institution: | Tuberculosis Research Unit, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, RE 113/213C, Boston MA 02115, USA. zchen@caregroup.harvard.edu |
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| Abstract: | Vgamma2Vdelta2(+) T cells exist only in primates and constitute the majority of circulating human gammadelta T cells. Recent studies have demonstrated that this unique gammadelta T cell subpopulation can be a component of adaptive immune responses and contribute to anti-microbial immunity to infections. |
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