Bioeffector Sphingolipids as Stimulators of Cell Growth and Survival |
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| Authors: | E. V. Dyatlovitskaya A. G. Kandyba |
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| Affiliation: | (1) Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, ul. Miklukho-Maklaya 16/10, GSP, Moscow, 117997, Russia |
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| Abstract: | The effects of various bioactive sphingolipids (sphingosine 1-phosphate, sphingosine 1-phosphocholine, ceramide 1-phosphate, ceramide  -glucoside and -lactoside, and gangliosides) on cell proliferation and apoptosis are reviewed. It is concluded that the balance between the bioeffector sphingolipids determines their overall effect on cell. |
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| Keywords: | apoptosis ganglioside ceramide glucoside ceramide lactoside proliferation sphingosine 1-phosphate sphingosine 1-phosphocholine |
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