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Vasoactive intestinal polypeptide (VIP) immunoreactivity of endocrine-like cells in the feline pyloric mucosa |
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| Authors: | Dr. J. Yamada N. Kitamura T. Yamashita M. Misu N. Yanaihara |
| Affiliation: | (1) Department of Veterinary Anatomy, Obihiro University of Agriculture and Veterinary Medicine, Obihiro;(2) Laboratory of Bioorganic Chemistry, Shizuoka College of Pharmacy, Shizuoka, Japan;(3) Department of Veterinary Anatomy, Obihiro University of Agriculture and Veterinary Medicine, Inada-cho, 080 Obihiro, Japan |
| Abstract: | Summary Immunoreactivity to VIP by endocrine-like cells in the feline pyloric mucosa was examined by using three kinds of region-specific anti-porcine VIP sera. VIP-immunoreactive endocrine-like cells were detected clearly with all of the VIP antisera used. They were located mainly around the neck of the pyloric glands. Some of these endocrine-like cells showed dilution-dependent immunoreactivity against VIP antisera. The immunostaining intensity of VIP-immunoreactive endocrine-like cells showing dilution-independence could not be distinguished from those of nerve elements. The present results suggest that the immunoreactivity with properties very similar to those of authentic VIP may be present in the endocrine-like cells of the feline pyloric glands. |
| Keywords: | Immunocytochemistry Vasoactive intestinal polypeptide Brain-gut peptide Pyloric antrum Cat |
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