Molecular mechanism of facilitated transport by carrier ionophores:a study of energetics |
| |
Authors: | N. Sreerama Saraswathi Vishveshwara |
| |
Affiliation: | (1) Molecular Biophysics Unit, Indian Institute of Science, 560 012 Bangalore, India |
| |
Abstract: | The mechanism of ion transport by carrier ionophores is investigated. The electrostatic potential is used as index of the binding energy of a cation with valinomycin and enniatin B. The ion binding capacities of these ionophores are studied as functions of conformation and of distance of an approaching ion-complex. The energetics of dirnerisation and the binding energy profile of an ion in dimers of valinomycin and enniatin B are examined. The binding energy profiles and the electrostatic potential surfaces of valinomycin and enniatin B are compared in relation to their biological activities. |
| |
Keywords: | Ion-transport valinomycin enniatin B binding energy electrostatic potential |
本文献已被 SpringerLink 等数据库收录! |