| Human chromosome pellicle antibody recognizing centromere protein—C （CENP0C）,the main component of the kinetochore |
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| 引用本文： | XIEYONG ZUMEINI 等.Human chromosome pellicle antibody recognizing centromere protein—C （CENP0C）,the main component of the kinetochore[J].细胞研究,1997,7(1):13-19. |
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| 作者姓名： | XIEYONG ZUMEINI |
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| 作者单位： | [1]HongKongUniversityofScienceandTechnology,DepartmentofBiology,HongKong [2]ShanghaiInstituteofCellBiology, |
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| 摘 要： | Recently the antichromosome antisera from several sclerogerma patients have been found to recognize the pellicle of metaphase and anaphase chromosomes.In order to identify the pellicle components,we used these antichromosome antisera to screen a human embryonic cDNA library.The sequences of the positive clones are identical to the cDNA gene sequence of CENP-C (centromere protein C),a human centromere autoantigen.This result suggusts that CENP-C is a component of the pellicle of human metaphase and anaphase chromosomes.
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| 关 键 词： | 动物细胞 动原体组件 染色体被膜抗体 鉴定 着丝点蛋白C 人硬皮病抗血清 |
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