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Transcriptional analysis of genes encoding Shiga toxin 2 and its variants in Escherichia coli
Authors:Zhang Wenlan  Bielaszewska Martina  Friedrich Alexander W  Kuczius Thorsten  Karch Helge
Affiliation:Institut für Hygiene, Universitätsklinikum Münster, Münster, Germany
Abstract:Six of 37 non-O157 Escherichia coli strains possessing Shiga toxin (Stx) 2 gene variant stx(2d) or stx(2e) secreted no detectable Stx. These isolates produced significantly less stx mRNA than Stx2d, Stx2e, Stx2c, or Stx2 secretors did. Standard screening procedures miss a significant subset of E. coli harboring stx(2) variants.
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